产品货号:
Z19498
中文名称:
Kv1.3/KCNA3抗体
英文名称:
Anti-Kv1.3/KCNA3 Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-Kv1.3/KCNA3 Antibody |
指标别名 | HGK5;HLK3;HPCN3;HUKIII;KCNA3;Kv1.3;MK3;PCN3 |
克隆性 | Polyclonal |
检验物种 | human,mouse,rat |
应用范围 | WB |
基因名称 | KCNA3 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | A synthetic peptide corresponding to a sequence at the C-terminus of human KCNA3 (513-544aa EELRKARSNSTLSKSEYMVIEEGGMNHSAFPQ),identical to the related mouse and rat sequences. |
实际分子量 | 55KD |
成分 | 500μg/mL antibody with PBS,0.02% NaN3,1mg BSA and 50% glycerol. |
纯化方式 | Immunogen affinity purified. |
浓度 | 500μg/mL |
产品形态 | 溶液 |
保存条件 | 12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
背景资料 | Potassium voltage-gated channel,shaker-related subfamily,member 3,also known as KCNA3 or Kv1.3,is a protein that in humans is encoded by the KCNA3 gene.This gene encodes a member of the potassium channel,voltage-gated,shaker-related subfamily.This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment.It belongs to the delayed rectifier class,members of which allow nerve cells to efficiently repolarize following an action potential.It plays an essential role in T-cell proliferation and activation.This gene appears to be intronless and it is clustered together with KCNA2 and KCNA10 genes on chromosome 1.And Kv1.3 has been reported to be expressed in the inner mitochondrial membrane in lymphocytes.The apoptotic protein Bax has been suggested to insert into theouter mitochondrial membrane and occlude the pore of Kv1.3 via a lysine residue.Thus,Kv1.3 modulation may be one of many mechanisms that contribute to apoptosis. |
Uniprot ID | P22001 |
推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
基因名全称 | potassium channel,voltage gated shaker related subfamily A,member 3 |
蛋白名全称 | Potassium voltage-gated channel subfamily A member 3 |
推荐稀释比 | Western blot(WB) 1:500~2000 |
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